陈尚宾

chenshangbin

职称

副教授

联系方式

电话 027-87792033-307
手机 
传真 027-87792034
邮箱 sbchen@mail.hust.edu.cn

教育背景

博士 2002-2006 生物医学工程 华中科技大学生命科学与技术学院
硕士 2001-2002 生物医学工程 华中科技大学生命科学与技术学院
学士 1997-2001 物理学 湖北师范学院物理系

工作经历

2006-2013 讲师 华中科技大学
2014-Now 副教授 华中科技大学武汉光电国家实验室

专业活动及社会服务

博士后 英属哥伦比亚大学(2010-2012)

研究兴趣

个人研究兴趣主要有:脑功能(光学成像、光基因)、脑连接(扩散磁共振成像和显微术)、皮层扩散性抑制和局灶性脑缺血、图像和数据处理。当前聚焦于脑连接研究。

期刊论文

1.Chen Shangbin, Mohajerani M., Xie Y., Murphy T*. Optogenetic analysis of neuronal excitability during global ischemia reveals selective deficits in sensory processing following reperfusion in mouse cortex. Journal of Neuroscience, 2012, 32(39):13510–13519.
2.Xie Yicheng1,Chen Shangbin1, Wu Y., Murphy T*. Prolonged deficits in Parvalbumin neuron stimulation-evoked network activity despite recovery of dendritic structure and excitability in the domatosensory cortex following global ischemia in mice. Journal of Neuroscience, 2014, 34(45):14890 –14900. (1, contributed equally)
3.Li Bing, Shangbin Chen*,Li Pengcheng, Luo Qingming,Gong Hui. Refractory period modulates the spatiotemporal evolution of cortical spreading depression: a computational study. PLoS One, 2014, 9(1): e84609.
4.Chen Shangbin, Sherri T., Sigler A., Murphy T*. Automated and quantitative image analysis of ischemic dendritic blebbing using in vivo 2-photon microscopy data. Journal Neuroscience Methods, 2011,195: 222–231.
5.Yang Wanneng, Xu Xiaochun, Bi Kun, Zeng Shaoqun, Liu Qian, Chen Shangbin*. Adaptive region of interest method for analytical micro-CT reconstruction. Journal of X-Ray Science and Technology, 2011, 19(1): 23-33.
6.Zeng Shuai, Li Bing, Zeng Shaoqun, Chen Shangbin*. Simulation of spontaneous Ca2+ oscillations in astrocytes mediated by voltage-gated calcium channels. Biophysical Journal, 2009, 97: 2429–2437.
7.Chen Shangbin, Li Pengcheng, Gong Hui, Zhang Yuhui, Zeng Shaoqun, Luo Qingming*. Monitoring biparietal cortical spreading depression in rats with optical intrinsic signal imaging, IEEE Engineering in Medicine and Biology, 2008, 27:29-35
8.Chen Shangbin1, Li Pengcheng1, Weihua Luo, Hui Gong, Shaoqun Zeng, Qingming Luo*. Time-varying spreading depression waves in rat cortex revealed by optical intrinsic signal imaging, Neurosci. Lett.2006, 396, 132–136.
9.Chen Shangbin, Feng Zhe, Li Pengcheng, Jacques S.L., Zeng Shaoqun, Luo Qingming*. In vivo optical reflectance imaging of spreading depression waves in rat brain with and without focal cerebral ischemia,J. Biomed. Opt. 2006, 11(3), 034002-1-13.
10.Chen Shangbin1, Li Pengcheng1, Luo Weihua, Gong Hui, Zeng Shaoqun, Luo Qingming*. Origin sites of spontaneous cortical spreading depression migrated during focal cerebral ischemia in rats, Neurosci.Lett. 2006, 403, 266–270.

荣誉及奖励

参与脑功能光学成像工作曾获2007年湖北省自然科学一等奖(排名5)。

在研或已完成的科研项目

1. 已主持完成国家自然科学基金项目: 基于皮层扩散性抑制信号的局灶性脑缺血研究(30800313, 2009-2011)。
2. 主持在研国家自然科学基金项目: 扩散MRI纤维示踪术的真实精细神经纤维构筑研究(61371014, 2014-2017)。