龚辉

gonghui

职称

教授

联系方式

电话 (86) 27 8779 2033
手机 
传真 (86) 27 8779 2034
邮箱 huigong@mail.hust.edu.cn

教育背景:

学士 1982-1986 红外技术 西北电讯工程学院(现西安电子科技大学)技术物理系

工作经历:

11/2011至今        教授       生物医学光子学,武汉光电国家实验室,华中科技大学 (HUST)
08/200011/2011     副教授     生物医学工程 (生物医学光子学),HUST
02/199908/2000     讲师       生物医学工程,生命学院, HUST
08/199301/1999     讲师       光电工程,光电子工程系,HUST
08/198608/1993     工程师     四川重庆光电技术研究所

研究兴趣:

长期从事发展光电新技术新方法以满足生物医学需求的研究,研究方向包括:1)脑结构与脑网络连接的光学成像研究,包括显微光学切片断层成像获取鼠脑高分辨图谱及脑神经连接等;2)近红外光学联合脑电的多模式功能成像研究。

期刊论文:

1. Hanqing Xiong, Zhenqiao Zhou, Mingqiang Zhu, Xiaohua Lv, Anan Li, Shiwei Li, Longhui Li, Tao Yang, Siming Wang, Zhongqin Yang, Tonghui Xu, Qingming Luo, Hui Gong*, Shaoqun Zeng*, Chemical reactivation of quenched fluorescent protein molecules enables resin-embedded fluorescence microimaging, Nature Communications, 2014, 5: 3992, doi: 10.1038/ncomms4992
2. Jingpeng Wu, Yong He, Zhongqin Yang, Congdi Guo, Qingming Luo, Wei Zhou, Shangbin Chen, Anan Li, Benyi Xiong, Tao Jiang, Hui Gong*, 3D BrainCV: Simultaneous visualization and analysis of cells and capillaries in a whole mouse brain with one-micron voxel resolution, NeuroImage, 2014, 87: 199-208
3. Bailei Sun, Lei Zhang, Hui Gong, Jinyan Sun, Qingming Luo*, Detection of optical neuronal signals in the visual cortex using continuous wave near-infrared spectroscopy, NeuroImage, 2014, 87: 190-198
4. Tingwei Quan, Jing Li, Hang Zhou, Shiwei Li, Ting Zheng, Zhongqing Yang, Qingming Luo, Hui Gong*, Shaoqun Zeng*, Digital reconstruction of the cell body in dense neural curcuits using a spherical-coordinated variational model, Scientific Reports, 2014, 4:4970, doi:10.10.8/srep04970
5. Lei Zhang, Jinyan Sun, Bailei Sun, Qingming Luo, Hui Gong*, Studying hemispheric laterlization during a Stroop task through near-infrared spectroscopy-based connectivity, Journal of Biomedical Optics, 2014, 19(5): 057012
6. Hui Gong1, Shaoqun Zeng1, Cheng Yan, Xiaohua Lv, Zhongqin Yang, Tonghui Xu, Zhao Feng, Wenxiang Ding, Xiaoli Qi, Anan Li, Jingpeng Wu, Qingming Luo*, Continuously tracing brain-wide long-distance axonal projections in mice at a one-micron voxel resolution, NeuroImage, 2013, 74: 87-98
7. Ting Zheng, Zhongqing Yang, Anan Li, Xiaohua Lv, Zhenqiao Zhou, Xiaojun Wang, Xiaoli Qi, Shiwei Li, Qingming Luo, Hui Gong*, Shaoqun Zeng*, Visualization brain circuits using two-photon fluorescence micro-optical sectioning tomography, Optics Express, 2013 21(8): 9839-9850.  
8. Zhongqin Yang, Bihe Hu, Yuhui Zhang, Qingming Luo, Hui Gong*, Development of a plastic embedding method for large-volume and fluorescent-protein-expressing tissues, PLoS One, 2013, 8(4): e60877     
9. Cheng Yan, Anan Li, Bin Zhang, Wenxiang Ding, Qingming Luo, Hui Gong*, Automated and accurate detection of soma location and surface morphology in large-scale 3D neuron images, PLoS One, 2013, 8(4): e62579.  
10. Tingwei Quan, Ting Zheng, Zhongqing Yang, Wenxiang Ding, Shiwei Li, Jing Li, Hang Zhou, Qingming Luo, Hui Gong*, Shaoqun Zeng*,NeuroGPS: automated localization of neurons for brain circuits using L1 minimization model, Scientific Reports, 2013, 3, 1414, DOI:10.1038/ srep01414  
11. Jinyan Sun, Bailei Sun, Lei Zhang, Qingming Luo, Hui Gong*. Correlation between hemodynamic and electrophysiological signals dissociates neural correlates of conflict detection and resolution in a Stroop task: a simultaneous near-infrared spectroscopy and event-related potential study. Journal of Biomedical Optics, 2013, 18(9), 096014-1-9.
12. Jiangbo Pu, Hui Gong, Xiangning Li, Qingming Luo, Developing neuronal networks: self-organized criticality predicts the future, Scientific Reports, 2013, 3: 1081, DOI: 10.1038/srep01081
13. Zhongxing Zhang, Bailei Sun, Hui Gong, Lei Zhang, Jinyan Sun, Bangde Wang, Qingming Luo, A fast neuronal signal-sensitive continuous-wave near-infrared imaging system, Review of Scientific Instruments, 2012, 83, 094301-1-094301-9
14. Guotao Quan, Hui Gong*, Yong Deng, Jianwei Fu, Qingming Luo, Monte Carlo-based fluorescence molecular tomography reconstruction method accelerated by a cluster of graphic processing units, Journal of Biomedical Optics, 2011, 16(2), 026018-1-026018-8 
15. Jianwei Fu, Xiaoquan Yang, Kan Wang, Qingming Luo, Hui Gong*, A generic, geometric co-calibration method for a combined system of fluorescence molecular tomography and micro-computed tomography with arbitrarily shaped objects, Medical Physics, 2011, 38(12), 6561-6570
16. Bin Zhang, Anan Li, Zhongqin Yang, Jingpeng Wu, Qingming Luo, Hui Gong*, Modified Golgi-Cox method for micrometer scale sectioning of the whole mouse brain, Journal of Neuroscience Methods, 2011, 197, 1-5
17. Anan Li1, Hui Gong1, Bin Zhang1, Qingdi Wang, Cheng Yan, Jingpeng Wu, Qian Liu, Shaoqun Zeng, Qingming Luo*, Micro-optical sectioning tomography to obtain a high-resolution atlas of the mouse brain, Science, 2010, 330(6009), 1404-1408
18. Ting Li, Qingming Luo, Hui Gong*, Gender-specific hemodynamics in prefrontal cortex during a verbal working memory task by near-infrared spectroscopy, Behavioural Brain Research, 2010, 209, 148-153
19. Jiahuan Zhai, Ting Li, Zhongxing Zhang, Hui Gong*, Hemodynamic and electrophysiological singnals of conflict processing in the Chinese-character Stroop task: a simultaneous near-infrared spectroscopy and event-related potential study, Journal of Biomedical Optics, 2009, 14(5), 054022

专利:

1. 骆清铭,龚辉,李婷,光在生物组织中传输特性的定量蒙特卡罗模拟方法,中国发明专利,授权时间(2009.12.30),专利号:ZL200810047962.7
2. 骆清铭、龚辉、张斌、李安安、王青蒂,一种精密扫描式切削系统及切削样本加工方法,中国发明专利,授权时间(2011.4.6),专利号:ZL200810306499.3
3. 骆清铭,龚辉,李婷,吕晓华,一种实现近红外脑功能检测仪测量同步的方法和装置,中国发明专利,授权时间(2011.5.25),专利号:ZL 200810306739.X
4. 骆清铭,龚辉,全国涛,邓勇,适于小动物的荧光分子层析成像方法,中国发明专利,授权时间(2011.9.28),专利号:ZL200910061250.5
5. 骆清铭,龚辉,李婷,获取稳态/瞬态光漫射特性的分析系统及方法,中国发明专利,授权时间(2011.10.26),专利号:ZL 200910300161.1
6. 骆清铭,李安安,张斌,杨中琴,龚辉,一种显微光学扫描层析成像装置,中国发明专利,授权时间(2012.10.31),专利号:ZL200910300483.6
7. 骆清铭,龚辉,张中兴,李婷,一种光学多参数生理检测仪,中国发明专利,授权时间(2011.5.25),专利号:ZL200910303109.1
8. 骆清铭,龚辉,杨孝全,全国涛,邓勇,一种活体小动物成像系统及成像方法,授权时间(2012.1.11),专利号:ZL200910306890.8
9. 骆清铭,龚辉,张中兴,何勇,一种光纤近红外光谱检测仪,中国发明专利,授权时间(2012.7.4),专利号:ZL201010200035.1 
10. 骆清铭,龚辉,傅建伟,杨孝全,X射线和荧光双模式活体成像系统的几何校准方法,中国发明专利,授权时间(2014.8.6),专利号:ZL201110293263.2
11. 骆清铭,杨孝全,龚辉,一种用于消除层析成像中环状伪影的方法及系统,中国发明专利,授权时间(2013.9.25),专利号:ZL201110293269.X 
12. 骆清铭,龚辉,邓子林,杨孝全,一种光声显微成像的自适应图像重建方法,中国发明专利,授权时间(2013.9.11),专利号:ZL201110392620.0  
13. 骆清铭,龚辉,许冬力,李安安,一种大样本快速三维显微成像的方法和系统,中国发明专利,授权时间(2014.10.19),专利号:ZL201210402820.4

荣誉及奖励:

  • 研究成果“显微光学切片断层成像获取小鼠全脑高分辨率图谱”入选“2011年度中国科学十大进展”。
  • 荧光显微光学切片断层成像成果入选“2013中国光学重要成果”。
  • 荣获2014年国家技术发明奖二等奖“单细胞分辨的全脑显微光学切片断层成像技术与仪器”(第2完成人)。

在研或已完成的科研项目:

  • 灵长类单细胞分辨神经回路的MOST成像,国家重点基础研究发展计划(973课题)课题负责人,2015.01-2019.08
  • 全脑尺度获取小鼠情感与记忆神经环路三维精细图谱的方法研究,国家自然科学基金,项目负责人,2015.01-2017.12