职称职务
博士、博士生导师、华中学者特聘岗位教授,武汉光电国家实验室生物医学光子学功能实验室副主任
联系方式
电话 (86) 27 8779 2033-302
手机
传真 (86) 27 8779 2034
邮箱 dawnzh@mail.hust.edu.cn
教育经历:
1982.9-1986.6:湖北大学物理系学习,获物理学理学学士
1989.9-1992.6:华中师范大学物理系学习,获无线电电子学理学硕士学位
1998.9-2001.8:华中科技大学光电子工程系学习,获电子科学与技术工学博士学位
工作经历:
2007.10-至今:华中科技大学武汉光电光国家实验室教授
2003.6-2007.10: 华中科技大学生命科学与技术学院副教授
2005.9-11: 俄罗斯萨拉托夫国立大学高级访问研究员
2001.8-2003.6:华中科技大学生物医学工程博士后流动站博士后
1992.6-1998.8:武汉理工大学(原武汉汽车工业大学电子电气工程系)讲师
1986.6-1989.8: 长江大学(原湖北农学院基础部)助教
主要学术兼职:
中国光学学会生物医学光子学专业委员会副主任委员、兼秘书长;
中国生物医学工程学会生物医学光子学分会常委;
曾任国家自然科学基金委重大科学仪器、科学部数字诊疗专项会评专家。
国际期刊编委:Scientific Reports、Journal of Innovative Optical Health Sciences、Frontier of Optoelectronics、Journal of Biomedical Photonics & Engineering
国际期刊客座编辑:Journal of Biomedical Optics, Journal of Innovative Optical Health Sciences、Frontier of Optoelectronics, Lasers & Photonics in Medicine
研究领域及主要研究进展:
一直从事组织光学成像新原理、新技术与新方法研究,近年来的主要研究兴趣集中于组织光透明研究。率先在国际上开展了在体光透明研究,发展了高效、安全的皮肤、颅骨光透明方法,能高分辨地获取皮下/皮层血管结构与功能信息,极大地提升了多种光学成像在活体应用能力。在国内外学术刊物上发表论文140余篇,其中80余篇被SCI、EI收录(含邀请综合评述2篇),参编国外专著中1章;应邀在国际国内学术会议上做邀请报告20余次;获授权国家发明专利3项。
近五年发表期刊论文(第一或通讯作者论文):
[1]Xiaoquan Yang, Yang Zhang, Kai Zhao, Yanjie Zhao, Yanyan Liu, Hui Gong, Qingming Luo*, and Dan Zhu*, Skull optical clearing solution for enhancing ultrasonic and photoacoustic imaging, IEEE Transactions on Medical Imaging, 99, 2016, 10.1109/TMI.2016.2528284
[2]Tingting Yu, Yisong Qi, Jianru Wang, Wei Feng, Jianyi Xu, Jingtan Zhu, Yingtao Yao, Hui Gong, Qingming Luo, Dan Zhu*, Rapid and prodium iodide-compatible optical clearing method for brain tissue based on sugar/sugar-alcohol, Journal of Biomedical Optics, 21(8), 081203-1-7, 2016
[3]Wei Feng, Rui Shi, Ning Ma, Daria K. Tuchina, Valery V. Tuchin, and Dan Zhu*,Skin Optical Clearing Potential of Disaccharides,21(8), 2016
[4]Rui Shi, Min Chen, Valery Tuchin and Dan Zhu*, Accessing to arteriovenous blood flow dynamics response using combined laser speckle contrast imaging and skin optical clearing, Biomedical Optics Express, 6 (6):1977-1989, 2015.
[5]Caihua Liu, Yue Guan, Jianru Wang, Xiewei Zhong, Xiuli Liu, Dan Zhu*, Reflectance spectroscopy for noninvasive evaluation of hair follicle stage, Journal of Biomedical Optics, 20(5), 051011-1-7, 2015
[6]Caihua Liu, Rui Shi, Min Chen and Dan Zhu*, Quantitative evaluation of enhanced laser tattoo removal by skin optical clearing, Journal of Innovative Optical Health Sciences, 8(3), 1541007, 2015
[7]Yang Zhang, Chao Zhang, Xiewei Zhong, Dan Zhu*, Quantitative evaluation of SOCS-induced optical clearing efficiency of skull, Quantitative imaging in medicine and surgery, 5(1): 136-142, 2015
[8]Xiewei Zhong, Shenxia Tan, Xiang Wen, Dan Zhu*, Effect of light beam on measurements of reflectance and transmittance of turbid media with integrating sphere: Monte Carlo simulation, Frontiers of Optoelectronics, 8: 203-211, 2015
[9]Jing Wang, Yang Zhang, Pengcheng Li, Qingming Luo, Dan Zhu*, Review: Tissue Optical Clearing Window for Blood Flow Monitoring, IEEE Journal of Selected Topics in Quantum Electronics, 20(2): 6801112, 2014
[10]Jing Wang, Ning Ma, Rui Shi, Yang Zhang, Tingting Yu and Dan Zhu*, Sugar-induced Skin Optical Clearing: From Molecular Dynamics Simulation to Experimental Demonstration, IEEE Journal of Selected Topics in Quantum Electronics, 20(2): 7101007, 2014
[11]Xiewei Zhong, Xiang Wen, and Dan Zhu*, Lookup-table-based inverse model for human skin reflectance spectroscopy: two-layered Monte Carlo simulations and experiments, Optics Express, 22(1): 1852-1864, 2014
[12]Xiang Wen, Xiewei Zhong, Tingting Yu, Dan Zhu*, A Monte Carlo based lookup table for spectrum analysis of turbid media in the reflectance probe regime, Quantum Electronics, 44(7): 641-645, 2014
[13]Dan Zhu*, Kirill V. Larin, Qingming Luo, and Valery V Tuchin*, Recent progress in Tissue optical clearing, Laser & Photonics Reviews, 7(5), 732-757, 2013.
[14]Yang Zhang, Yongjun Chen, Yuan Yu, Xingbo Xue, Valery V. Tuchin, and Dan Zhu*, Visible and near-infrared spectroscopy for distinguishing maligna nt tum or tissue from benign tum or and normal breast tissues in vitro, Journal of Biomedical Optics, 18(7), 077003 (2013)
[15]Caihua Liu, Jie Zhang, Yuanlei Yue, Qingming Luo, Dan Zhu*, 1064 nm-Nd: YAG lasers with different output modes enhancing transdermal delivery- physical and physiological mechanisms, Journal of Biomedical Optics, 18(6), 061228 (2013).
[16]Jing Wang, Rui Shi, Dan Zhu*,Switchable skin window induced by optical clearing method for dermal blood flow imaging,Journal of Biomedical Optics, 18(6), 061209 (2013)
[17]Jing Wang, Rui Shi, Dan Zhu*, Ear skin optical clearing for improving blood flow imaging, Lasers & Photonics in Medicine, 2(1): 37-44, 2013
[18]Yimin Ding, Jing Wang, Zhichao Fan, Dan Wei, Rui Shi, Qingming Luo, Dan Zhu*, and Xunbin Wei*, Signal and depth enhancement for in vivoflow cytometer measurement of ear skin by optical clearing agents, Biomedical Optics Express, 4(11), 2518-2526(2013)
[19]Jing Wang, Yang Zhang,Tonghui Xu,Qingming Luo,Dan Zhu*,An innovative transparent cranial window based on skull optical clearing,Laser Physics Letters 9(6), 469-473, 2012
[20]Xiang Wen, Steven L Jacques, Valery V Tuchin, Dan Zhu*,Enhanced optical clearing of skin in vivo and OCT in-depth imaging,Journal of Biomedical Optics, 17(6), 066022, 2012
参编书稿:
[21]Dan Zhu, Qingming Luo and Valery Tuchin, Tissue Optical Clearing, in Advanced Biophontonics-Tissue Optical Sectioning, edited by Ruikang Wang, Valery Tuchin, CRC Press, Chapter 17, 621-672, 2013
组织专刊:
[22]Dan Zhu, Bernard Choi, Elina, Valery Tuchin, Tissue and Blood Optical Clearing for Biomedical Applications, Journal of Biomedical Optics, 21(8), 081201, 2016
[23]Dan Zhu, Shaoqun Zeng, Valery Tuchin, A special issue on Biomedical Photonics, Frontiers of Optoelectronics, 8(2), 2015
[24]Kirill V. Larin, Dan Zhu, Foreword to the Special Issue Celebrating Prof. Valery Tuchin's 70th Birthday, Journal of Innovative Optical Health Sciences, 8(3), 2015
[25]Elina A. Genina, Dan Zhu; Valery V. Tuchin, Foreword to the Special Issue on Optical Technologies in Biophysics and Medicine, Journal of Innovative Optical Health Sciences, 8(3), 2015
[26]Dan Zhu, Qingming Luo, Current research on photonics and lasers in medicine in China, Photonics & Lasers in Medicine, 2(1): 1-3, 2013
[27]Dan Zhu, Valery Tuchin, Qingming Luo, Introduction: special issue on advances in biophotonics and biomedical optics - part II, Journal of Innovative Optical Health Sciences, 6(2), 2013
[28]Dan Zhu, Valery Tuchin, Qingming Luo, Introduction: special issue on advances in biophotonics and biomedical optics - part I, Journal of Innovative Optical Health Sciences, 6(1), 2013
近五年主持在研或完成的科研项目
1)国家自然科学基金面上项目:组织光透明结合光学成像获取周围神经系统整体三维结构: 从终末效应器、神经干到脊髓(No.31571002)(2016.1-2019.12)
2)国家自然科学基金重大研究计划培育项目:基于光透明的稳定颅窗实施穿颅活体皮层光学成像研究 (N0. 91232710)(2013.1-2015.12)
3)国家自然科学基金面上项目:在体皮肤光透明机制的定量研究(No. 81171376)(2012.1-2015.12)
4)国家自然科学基金国际合作与交流项目:正常与病理状态下皮肤光透明机制的定量研究(No.812111313)(2013.1-2014.12)
教育部博士点基金:用分子动力学与高光谱成像研究在体皮肤光透明机制(No.20110142110073)(2012.1-2014.12)