报告题目：表面增强拉曼光谱在细胞生物和电化学研究中的应用
Application of Surface Enhanced Raman Spectroscopy in Cell Biology and Electrochemistry
时 间：2019年1月4日14:30-16:00
地 点：光电国家研究中心A101
报 告 人：任 斌 教授， 厦门大学
邀 请 人：王 平 教授
报告人简介（Biography）：
任斌教授，分别于1992年和1998年在厦门大学化学系获得学士和博士学位。现任厦门大学化学化工学院副院长，固体表面物理化学国家重点实验室副主任，美国化学会Analytical Chemistry期刊副主编。主要从事针尖增强拉曼光谱（TERS）、表面增强拉曼光谱（SERS）以及纳米和光谱电化学新方法的发展、仪器研制及其在表、界面过程及细胞生物体系的应用研究。获得国家基金重点项目、重大项目和科学仪器基础专项以及科技部重大仪器设备开发专项和重大科学研究计划课题等基金项目的资助。迄今已发表SCI论文200多篇，包括Nature Nanotechnol.、Nature Commun.、JACS、Angew. Chem.、Chem. Rev., Chem. Soc. Rev.等期刊，他引14000余次。2002-2003年受洪堡基金（AvH）资助在德国Fritz-Haber研究所从事科研合作，2008年获国家杰出青年科学基金，2016年入选第二批国家“万人计划”科技创新领军人才和教育部“长江学者”特聘教授。
Professor Ren Bin received his bachelor's degree and doctor's degree from the Department of Chemistry, Xiamen University in 1992 and 1998, respectively. He is currently the Vice Dean of the College of Chemistry and Chemical Engineering, Xiamen University, Vice Director of the State Key Laboratory of Physical Chemistry of Solid Surfaces and Associate Editor of Analytical Chemistry, American Chemical Society. He is mainly engaged in the development of Tip-enhanced Raman spectroscopy (TERS), surface-enhanced Raman spectroscopy (SERS), new methods of nanochemistry and spectroelectrochemistry, instrumentation and their applications in surface, interface processes and cell and biological systems. He has been supported by key projects of scientific instruments of NSFC, as well as projects of major instruments and equipment development and major scientific research projects of the Ministry of Science and Technology. He has published more than 200 SCI papers, including Nature Nanotechnol., Nature Commun., JACS, Angew. Chem., Chem. Rev., Chem. Soc. Rev., with more than 14,000 citations. In 2002-2003, he was funded by Alexadner von Humboldt Foundation to work at Fritz-Haber Institute in Germany. In 2008, he was awarded the National Outstanding Youth Science Fund. In 2016, he was selected as the second batch of national "ten thousand people plan" and the Changjiang Scholar professor of the Ministry of Education.
报告摘要（Abstract）：
表面增强拉曼光谱（SERS）利用Ag、Au等纳米结构，能显著增强吸附在纳米结构表面的分子的拉曼信号，并以超高表面灵敏度获得样品自身的指纹振动信息，是极具前景的表界面和生物分析检测技术。但是，由于生物细胞体系自身的复杂性，以及光-纳米材料表面-生物体系三者间异常复杂的相互作用，使得SERS检测结果的可靠性相对较差，也制约了其在生物医学领域内的广泛应用。本次报告将讨论SERS在生物检测中的可靠性问题，以及存在机遇和挑战。为了拓展拉曼光谱在电化学动态反应过程表征中的应用，我们建立了一种基于电化学表面增强拉曼光谱技术的电化学显微镜，可以在电化学反应过程中，利用拉曼信号强度变化，重构电极表面分子局域的电化学电流，获得局域的电化学信息。
Surface-nhanced Raman Spectroscopy (SERS) is a promising technique, which utilizes nanostructures such as Ag and Au to enhance the Raman signal of molecules adsorbed on the surface of nanostructures and obtain the fingerprint vibrational information of samples with an ultra-high surface sensitivity. However, due to the complexity of biological systems and the extremely complex interaction between light, nanomaterial surface and biological system, the reliability of SERS is relatively poor, which also restricts its wide application in the field of biomedicine. This report will discuss the reliability of SERS in biological detection, as well as the opportunities and challenges. In order to expand the application of Raman spectroscopy in the characterization of electrochemical dynamic reaction processes, an electrochemical microscope on the basis of electrochemical surface-enhanced Raman spectroscopy (SERS) technology was established. The local electrochemical current of the molecule on the electrode surface could be reconstructed by the change of Raman signal intensity, and the local electrochemical information could be obtained during the process of electrochemical reaction.
